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Many men long for ways to lose weight in a hurry and get the trim physique they've always dreamed of. While there's no substitute for diet and exercise, there are certainly some safe and effective fat burners on the market that may give you that little extra push towards your weight loss goals.
The Best Weight Loss Supplements for Men - Our Top Picks
- Best Overall Weight Loss Supplement for Men: PhenQ
- Best Keto Weight Loss Supplement for Men: Hunter Burn
- Best Budget Weight Loss Supplement for Men: Instant Knockout Cut
- Best Weight Loss Supplement for Men Bodybuilding: Huge Supplements Stack
- Best Vegan Weight Loss Supplement for Men: Kaged Clean Burn Powder
- Best Thermogenic Weight Loss Supplement for Men: Capsiplex Burn
- Best Weight Loss Supplement for Men to Build Muscle: TestoPrime
- Best High-Quality Weight Loss Supplement for Men: PhenQ
- Best Weight Loss Supplement for Men Over 40: Phen24
But with so many weight loss supplements to choose from, how do you know which one is the best, healthiest option? We researched some of the top options and developed a condensed list of recommendations. These are our picks for the best weight loss supplements for men.
Why Trust Us?
The health and safety of ACTIVE's readers are of the utmost importance to us. To ensure your well-being when consuming weight loss supplements, the ACTIVE.com editorial team prioritizes products that are independently tested by a third party. We've also consulted with a team of nutritionists and dieticians to ensure the products we feature are of the highest standard. This helps us create the most accurate, authentic review content for our readers.
Disclaimer: Exercise caution when taking supplements. Always make sure to consult with your doctor before trying a new supplement or pill. Weight loss supplements are not a substitute for a balanced diet and regular exercise. Any supplements taken should be used in accordance with a healthy lifestyle. Any weight loss of more than a pound per week over a long period of time is unusual and should be monitored by a doctor.
Best Overall Weight Loss Supplement for Men - PhenQ
SPECS
- Dosage: 2 tablets per day
- Ingredients: Capsimax powder, chromium picolinate, caffeine
- Certifications: Vegetarian and vegan, manufactured in GMP-certified facility
Our best overall supplement for men wanting to lose weight is PhenQ. This is essentially the brand name for α-Lacys Reset®, a patented form of alpha-lipoic acid and cysteine that may help ramp up thermogenesis within your body (that is, it improves your body's ability to burn calories, kicking your metabolism into a higher gear).(1) Its unique combination of ingredients works to suppress your appetite, boost energy, and improve your mood—just what you need as you fire through tough workouts.
The zero carbs and calories paired with the capsaicinoids make it the ideal weight loss supplement to potentially help reduce excess body fat. It also contains about 75 milligrams of caffeine anhydrous. PhenQ is also vegan and vegetarian, and a single bottle contains enough doses to get you through an entire month.
What We Like
- May help boost metabolism, burn fat, suppress appetite, and increase energy
- Contains all-natural, research-backed ingredients
- Decent value
- Robust guarantee
What We Don't Like
- Not recommended if you're cautious about caffeine intake
- Claims to help build muscle, but there isn’t enough research to support this
Best Keto Weight Loss Supplement for Men - Hunter Burn
SPECS
- Dosage: 6 tablets per day
- Ingredients: Vitamin D3, konjac root extract, white kidney bean 20:1 extract, matcha green tea, cayenne pepper, L-theanine
- Certifications: non-GMO, manufactured in FDA GMP-compliant facility
Hunter Burn features combinations of six natural ingredients that fall into three categories: Hunger Neutralizer, Thermo-Burn, and Energy Unlock. The star of appetite suppressants—or "hunger neutralizers"—is Konjac root, a starchy root vegetable full of glucomannan soluble fiber. This fiber can help increase satiety, helping you stay fuller for longer, and is much lower in digestible carbs for those on the keto diet.(2) Similarly, white kidney bean extract is included as an additional carb blocker. As for the "burn," you'll be getting that from 125 grams of body temp elevating cayenne pepper and 200 milligrams of matcha green tea. Lastly, L-theanine and vitamin D3 are included to help support your energy levels for long training sessions without caffeine.
Hunter Burn is fairly expensive but does offer bundle discounts that include extras like video programs, nutritional e-books, and a 12-week transformation program. This product is also manufactured in a cGMP-regulated facility.
What We Like
- Natural ingredients for appetite suppression, thermogenesis, and energy
- Higher doses and science-backed formulas
- FDA GMP-compliant
- Caffeine-free
What We Don't Like
- 6 daily capsules can be a lot for some
- Expensive
Best Budget Weight Loss Supplement for Men - Instant Knockout Cut
SPECS
- Dosage: 1 capsule, 4 times per day
- Ingredients: Vitamin D3, vitamin B6, vitamin B12, caffeine, L-theanine, green tea extract, black pepper extract, glucomannan
- Certifications: Manufactured in cGMP-registered facility, vegan
Developed for professional boxers and MMA fighters looking to make weight—and endorsed by MMA coaches and fighters—Instant Knockout Cut is a punch to the gut in a fist-shaped container. It contains 100% natural—and familiar—ingredients to help suppress appetite, increase energy levels, and boost your metabolism, like cayenne pepper seeds, caffeine, and glucomannan.
Instant Knockout Cut might be considered an unconventional choice in the "best budget" category, but we ultimately chose it because of the BOGO bundle deal that gets you a free fourth box when you buy three (a four-month supply), the Boss Shred training program, and free shipping ($0.40 per capsule). A bundle like this may save you more over time, especially if your weight loss journey is a marathon, not a sprint. The full dosage is one capsule, four times daily, but if that feels daunting you might consider starting at a lower dose to gauge your tolerance.
What We Like
- Made with natural ingredients
- Trainer and fighter trusted
- Excellent bundle deal
- Vegan-friendly
What We Don't Like
- Some users may experience side effects like headaches, nausea, and difficulty sleeping
- Pills may be difficult to swallow
Best Weight Loss Supplement for Men Bodybuilding - Huge Supplements Enhanced Shredded Stack
SPECS
- Dosage: 3 capsules Exterminate (upon waking), 3 capsules of Eliminate (3 hours after taking Exterminate)
- Ingredients: Acetyl-l-carnitine, green coffee bean extract, caffeine anhydrous, L-theanine, L-tyrosine, capsaicin, huperzine A, BioPerine
- Certifications: Manufactured in FDA-regulated facility, GMP-certified
True to its name, the Huge Supplements Enhanced Shredded Stack is stacked with a combination of two popular Huge Supplements products, Exterminate and Eliminate. Both formulas are thermogenic and include ingredients for appetite suppression and energy and metabolism boosts, like multiple forms of caffeine, a capsaicin blend called Thermo V, and acetyl-l-carnitine for increased energy and metabolism function.(3)
These two formulas are potent enough for even the most seasoned bodybuilder looking to cut; however, it is highly recommended you start with 1 capsule of each product to assess your tolerance before graduating to the full 3 capsules daily dosage (6 capsules total). Also, be sure not to combine this stack with other products containing other stimulants like caffeine, as the levels in the Enhanced Shredded Stack are already high.
What We Like
- Formulated with bodybuilders in mind
- Both thermogenics have unique blends
- Highly rated among reviewers
- Transparent labeling
- Products are researched and tested
What We Don't Like
- Expensive
- You will likely run out of Exterminate before Eliminate
- May be too much caffeine for some
BUY: Huge Supplements Enhanced Shredded Stack
Best Vegan Weight Loss Supplement for Men - Kaged Clean Burn Powder
SPECS
- Dosage: 1 scoop
- Ingredients: L-carnitine, coconut fruit water powder, apple cider vinegar
- Certifications: Vegan
It's more than possible to find a vegan-friendly weight loss supplement, and our favorite is the powder-based Kaged Clean Burn Powder. Each scoop comes loaded with holistic ingredients like caffeine and organic apple cider vinegar, designed to stimulate energy, improve metabolism, and burn fat.(4)
While drinkable supplements aren't convenient for everyone, we will note that the orange mango flavor of this one is plenty palatable, making for a refreshing pre-workout ritual.
What We Like
- All vegan, organic ingredients
- Great flavor
- Helps boost metabolism and energy while burning fat
- Refreshing way to prepare for a workout
What We Don't Like
- Taking the time for dissolvable powders isn't always convenient
- Slightly higher price point
- No options in terms of flavor
Best Thermogenic Weight Loss Supplement for Men - Capsiplex Burn
SPECS
- Dosage: 3 capsules
- Ingredients: Capsimax®, Innoslim®, caffeine, B vitamins, iodine, chromium, tyrosine, arginine, black pepper
- Certifications: GMP-certified, vegan, gluten-free, made in FDA-approved facility
Many of the products on our list contain ingredients to help support thermogenesis, or the heating up of the body to produce energy and burn excess calories. We chose Capsiplex Burn for this category because it contains 100 milligrams per serving of Capsimax®, a patented form of cayenne pepper extract that is a powerful thermogenic agent.(5) It also contains another patented thermogenic blend called Innoslim® which combines astragalus and panax ginseng root.(6)
Aside from those standouts, Capsiplex Burn's list of ingredients is transparent, GMP-certified, and vegan-friendly. This formidable formula is also gluten, dairy, and soy-free.
What We Like
- Contains highly thermogenic ingredients
- Transparent labeling
- 60-day money-back guarantee
- Bundle discounts
What We Don't Like
- Caffeine level may be too high for some
- 3 capsules on an empty stomach won't work for all users
Best Weight Loss Supplement for Men to Build Muscle - TestoPrime
SPECS
- Dosage: 4 supplements daily
- Ingredients: D-aspartic acid, Panax ginseng, fenugreek
- Certifications: N/A
TestoPrime has a unique value proposition: It relies on natural ingredients to help boost natural testosterone levels, positioning it not only as a remedy for low T but also as a great way for guys to experience renewed energy and increased stamina. This may result in more potent workouts.
Best of all, this is one of the rare fat burners that help preserve muscle mass—a must for dudes who really want to look ripped, not just skinny.
What We Like
- Reasonable price point
- Great for men who want to maintain muscle mass
- All-natural ingredients
- Improves energy and stamina
- Lifetime guarantee
What We Don't Like
- 4 pills a day can be a lot to keep up with
- Not as helpful if you don't work out pretty consistently
Best High-Quality Weight Loss Supplement for Men - PhenQ
SPECS
- Dosage: 2 tablets per day
- Ingredients: Capsimax® powder, chromium picolinate, caffeine
- Certifications: Vegetarian and vegan, manufactured in GMP-certified facility
It should come as no surprise that our best overall weight loss supplement for men is also listed in the high-quality category. PhenQ includes a unique combination of natural metabolism-boosting ingredients that put in the hard work to help suppress appetite, boost energy, and improve mood. PhenQ is also vegan-friendly and has zero carbs or calories and 75 milligrams of caffeine per serving to help crush cravings.
What We Like
- Contains all-natural, research-backed ingredients
- May help boost metabolism, burn fat, suppress appetite, and increase energy
- Decent value
- Robust guarantee
What We Don't Like
- Not recommended if you're cautious about higher caffeine intake
- May cause side effects like nausea
Best Weight Loss Supplement for Men Over 40 - Phen24
SPECS
- Dosage: 1 capsule (day) 2 capsules (night)
- Ingredients: L-phenylalanine, guarana, cayenne, ashwagandha, L-theanine, L-arginine, choline bitartrate, griffonia
- Certifications: Vegan, manufactured in GMP-certified facility
With its day and night formulas, Phen24 is marketed as a 24-hour fat-burning system, all but guaranteed to help kick metabolism into gear, especially when it starts to slow down with age.
Phen24's Day Formula contains caffeine, guarana, and cayenne powder for a thermogenic metabolism boost and L-phenylalanine, which has been shown to have positive effects on appetite reduction and overall satiety.(7)
As for the night formula, Phen24 Night features ingredients like calcium D-pantothenate, choline, green tea extract, hops extract, and the dietary fiber glucomannan, well-known for its effects on increasing satiety levels.(8) When taken together—and in tandem with a well-balanced diet and exercise regimen—these fat-fighting formulas can be an effective weight-loss tool for men over 40.
What We Like
- Formulas for day and night
- Natural ingredients for appetite suppression
- Money-back guarantee
- Vegan-friendly
What We Don't Like
- Night formula does contain some caffeine
- No info on third-party testing
How Do Weight Loss Supplements Help You Burn Fat?
While weight loss supplements can vary in how they work, most of the good ones do three things at the same time: They enhance your metabolism, suppress your appetite, and burn fat. These functions can provide results all on their own, but they are really meant to augment your ongoing efforts at sound nutrition and consistent exercise.
How We Chose the Best Weight Loss Supplements for Men
The ACTIVE Reviews Team decided on our list of the best weight loss supplements for men by researching products from brands we trust with transparent ingredients and formulas, certifications, value for cost, and overall positive word-of-mouth from reviewers. We also consider brands/products with excellent track records for customer service or money-back guarantees.
How to Choose the Best Weight Loss Supplement for Men
As you seek the best weight loss supplement, there are several factors to consider.
Dosage
Just like other supplements for men, fat burners will have varying serving sizes. How many supplements will you need to take each day in order to achieve your desired outcomes? How many servings come in the bottle? And what's the total cost? These questions all get to the issue of overall value.
Guarantees
Keep in mind that fat burners are not intended to help you shed countless pounds overnight; in fact, losing weight too quickly would be adverse to your health. Instead, they help enhance the results of your regular diet and exercise, something that may take a few weeks or even a few months to generate results. Some products will come backed with guarantees, offering your money back if you don't see results in, say, 60 days.
Ingredients
Never take a supplement without knowing what's in it! Natural ingredients such as fiber, caffeine, and green tea extract are generally your best, healthiest bets. Also, try to find supplements that list the amount of each ingredient on the label.
Certifications
Looking for products that are sure to be all-organic? How about fat burners that are vegan? Make sure you get something that has the appropriate certification on the bottle.
Our Final Takeaway
We're realistic enough to know that weight loss isn't as easy as taking a pill; this is a list of suggestions to potentially help you cross the finish line for your fitness goals rather than an immediate solution. A well-balanced diet and regular exercise should always be your priority when trying to lose weight. Remember, consistency is key.
FAQs About Weight Loss Supplements for Men
What vitamins help burn fat?
Certain vitamins can help bolster your body's fat-burning abilities. Most effective are Niacin, iron, and the B-complex vitamins, particularly vitamin B-6.
Do weight loss supplements work?
Weight loss supplements that include proven, natural ingredients, and that are paired with diet and exercise, can certainly be effective. It's crucial to have realistic expectations, and not to anticipate stunning results overnight. Also, remember that there’s no substitute for a well-rounded diet and exercise so if you’re not doing these things, a supplement alone isn’t the solution.
Are weight loss supplements healthy?
Supplements that are based on all-natural ingredients can be healthy, though we would recommend checking with your doctor before you start taking anything, especially anything with a high concentration of caffeine.
Will weight loss supplements make me lose muscle?
Burning more calories almost always means a loss of muscle as well as fat. To maintain muscle tone, make sure you stay consistent with your strength-training workouts.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
References
- Namazi, N., Larijani, B., & Azadbakht, L. (2018). Alpha-lipoic acid supplement in obesity treatment: A systematic review and meta-analysis of clinical trials. Clinical nutrition (Edinburgh, Scotland), 37(2), 419–428. https://doi.org/10.1016/j.clnu.2017.06.002
- Keithley, J. K., Swanson, B., Mikolaitis, S. L., DeMeo, M., Zeller, J. M., Fogg, L., & Adamji, J. (2013). Safety and efficacy of glucomannan for weight loss in overweight and moderately obese adults. Journal of obesity, 2013, 610908. https://doi.org/10.1155/2013/610908
- National Institutes of Health (2023). Carnitine - Fact Sheet for Health Professionals. NIH Office of Dietary Supplements. Retrieved May 16, 2023, from https://ods.od.nih.gov/factsheets/Carnitine-HealthProfessional/
- Khezri, S.S., Saidpour, A., Hosseinzadeh, N., Amiri, Z. Beneficial effects of Apple Cider Vinegar on weight management, Visceral Adiposity Index and lipid profile in overweight or obese subjects receiving restricted calorie diet: A randomized clinical trial, Journal of Functional Foods, Volume 43, 2018, Pages 95-102, ISSN 1756-4646, https://doi.org/10.1016/j.jff.2018.02.003. (https://www.sciencedirect.com/science/article/pii/S1756464618300483)
- Janssens, P. L., Hursel, R., Martens, E. A., & Westerterp-Plantenga, M. S. (2013). Acute effects of capsaicin on energy expenditure and fat oxidation in negative energy balance. PloS one, 8(7), e67786. https://doi.org/10.1371/journal.pone.0067786
- Wu, S. H., Li, H. B., Li, G. L., Qi, Y. J., Zhang, J., & Wang, B. Y. (2020). Panax ginseng root, not leaf, can enhance thermogenic capacity and mitochondrial function in mice. Pharmaceutical biology, 58(1), 374–384. https://doi.org/10.1080/13880209.2020.1756348
- Fitzgerald, P. C. E., Manoliu, B., Herbillon, B., Steinert, R. E., Horowitz, M., & Feinle-Bisset, C. (2020). Effects of L-Phenylalanine on Energy Intake and Glycaemia-Impacts on Appetite Perceptions, Gastrointestinal Hormones and Gastric Emptying in Healthy Males. Nutrients, 12(6), 1788. https://doi.org/10.3390/nu12061788
- Keithley, J., & Swanson, B. (2005). Glucomannan and obesity: a critical review. Alternative therapies in health and medicine, 11(6), 30–34.