The Gennix TR1 Elite includes a Shimano Di2 Ultegra 6870 rear derailleur and, while not as light as its Dura-Ace counterpart, we found the shifting to be ultra-reliable, even when under load. We were impressed by the battery life, too--we only had to charge it after every five to six rides, and mostly just because we were nervous. Garneau cut costs by including a Shimano 105 cassette and, again, while not as light or crisp as an Ultegra or Dura-Ace option, you can always upgrade down the road.
The bike features a vertical rear dropout, which ultimately makes removing the wheel easier, but doesn't allow the wheel to be moved closer to the frame (aero penalty).